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KMID : 0876920040080020039
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Kwandong Medical Journal
2004 Volume.8 No. 2 p.39 ~ p.43
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Effect of Sodium Bicarbonate or Lidocaine Mixed with Rocuronium on Pain during Rocuronium Intravenous Injection
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Kim Yong-Ho
Choi Young-Soon
Lee Woo-Kyoung
Chae Young-Keun
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Abstract
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Background: Rocuronium produces intense pain on intravenous injection in conscious patients. The aim of this study was to evaluate the effectiveness of mixing rocuronium with sodium bicarbonate or lidocaine on the pain associated with intravenous administration of rocuronium in conscious patients.
Methods: Thirty patients who needed surgical procedure under general anesthesia were randomized into three groups. Group I received rocuronoium 50 mg plus saline 5 ml, group 2 received rocuronium 50 mg plus 2% lidocaine 2 ml plus saline 3 ml and group 3 received rocuronium 50 mg plus 8.4% sodium bicarbonate 3 ml plus saline 2 ml. The patients were then observed and asked if they experienced pain or discomfort during injection.
Results: The incidence rate of pain on injection of rocuronium was more reduced in group 2, and 3 than in group 1. Moderate to severe pain did not occur in group 3.
Conclusion: In conscious patients, mixing sodium bicarbonate with rocuronium is simple and effective for preventing pain during intravenous injection of rocuronium.
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KEYWORD
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rocuronium, pain, lidocaine, sodium bicarbonate
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